The below link will direct you to Tablets & Capsules Magazine.
In this article, HiSORAD was evaluated from the viewpoints of suitability as an ODT and applicability for direct compression. The placebo ODTs with HiSORAD showed satisfactory rapid disintegration and compactability without the addition of disintegrants or binders, maintaining the practical hygroscopic stability. Additionally, HiSORAD demonstrated the ability to load a high dose of APIs while maintaining high hardness and rapid disintegration. On the other hand, the content uniformity of direct-compression ODTs made with HiSORAD was evaluated using a lab-scale rotary tablet press. The result showed adequate content uniformity for the direct-compression process. Therefore HiSORAD provides not only good performance as ODTs, but also applicability for the direct-compression process.